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Therapeutic oligonucleotides : transcriptional and translational strategies for silencing gene expression / edited by Y.S. Cho-Chung, Alan M. Gewirtz, and Cy A. Stein.

By: (7th : NIH Symposium on Therapeutic Oligonucleotides (7th : 2004 : National Institutes of Health)
Contributor(s): Cho-Chung, Yoon S | Gewirtz, A. M. (Alan M.) | Stein, Cy A | New York Academy of Sciences
Material type: TextTextSeries: Annals of the New York Academy of Sciences, v. 1058Publisher: New York : New York Academy of Sciences, 2005Description: xvi, 266 p. : ill. ; 24 cmISBN: 1573316083 (cloth : alk. paper); 9781573316088 (cloth : alk. paper); 1573316091 (pbk. : alk. paper); 9781573316095 (pbk. : alk. paper)Subject(s): Oligonucleotides -- Therapeutic use -- Congresses | Oligonucleotides -- therapeutic use -- CongressesDDC classification: 615.31 LOC classification: Q11 | .N5 vol. 1058 | QP625.O47Other classification: 44.38 Online resources: Table of contents | Publisher description
Contents:
Knockdown of the cytoprotective gene, clusterin, to enhance hormone and chemosensitivity in prostate and other cancers / Martin Gleave -- Recognition of chromosomal DNA in human cells by peptide nucleic acids and small duplex RNAs / David R. Corey -- Design and development of thermolytic DNA oligonucleotide prodrugs / Andrzej Grajkowski ... [et al.] -- Rationally targeted, conformationally constrained, oxetane-modified oligonucleotides demonstrate efficient gene-silencing activity in a cellular system / J. B. Opalinska and A. M. Gewirtz -- In vivo potentialities of EWS-Fli-1 targeted antisense oligonucleotides-nanospheres complexes / Andrei Maksimenko ... [et al.] -- Endo-porter: a novel reagent for safe, effective delivery of substances into cells / James E. Summerton -- Tumor reversion: protein kinase a isozyme switching / Yoon S. Cho-Chung and Maria V. Nesterova -- Therapeutic potential of oligonucleotides expressing immunosuppressive TTAGGG motifs / Dennis M. Klinman ... [et al.] -- Breaking tolerance to tumors with dendritic cell-based immunotherapy / Ines Mende and Edgar G. Engleman --
Development of resistance to RNAi in mammalian cells / Zhi-Ming Zheng, Shuang Tang, and Mingfang Tao -- The development of bioactive triple helix-forming oligonucleotides / Michael M. Seidman ... [et al.] -- Transcription factor decoys: a new model for disease intervention / Michael J. Mann -- DNA damage produced by 125I-triplex-forming oligonucleotides as a measure of their succesful [sic] delivery into cell nuclei / Irina V. Panyutin -- Targeted genome modification via triple helix formation / Jennifer M. Kalish and Peter M. Glazer -- "Promoter array" studies identify cohorts of genes directly regulated by methylation, copy number change, or transcription factor binding in human cancer cells / Yipeng Wang ... [et al.] -- Application of expression genomics for predicting treatment response in cancer / Khew-Voon Chin ... [et al.] -- Stability regulation of mRNA and the control of gene expression / Chris Cheadle ... [et al.] -- Novel MDM2 p53-independent functions identified through RNA silencing technologies / Zhuo Zhang ... [et al.] -- Application of XIAP antisense to cancer and other proliferative disorders: development of AEG35156/ GEM 640 / Eric C. Lacasse ... [et al.] -- Induction of apoptosis by G3139 in melanoma cells / Luba Benimetskaya ... [et al.] -- Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy / Victor E. Marquez ... [et al.] -- Chemoprevention with protein kinase A RI[alpha] antisense in DMBA-mammary carcinogenesis / Maria V. Nesterova and Yoon S. Cho-chung.
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615.31 C.C.T 2015 (Browse shelf) Available 16198

Includes bibliographical references and index.

Knockdown of the cytoprotective gene, clusterin, to enhance hormone and chemosensitivity in prostate and other cancers / Martin Gleave -- Recognition of chromosomal DNA in human cells by peptide nucleic acids and small duplex RNAs / David R. Corey -- Design and development of thermolytic DNA oligonucleotide prodrugs / Andrzej Grajkowski ... [et al.] -- Rationally targeted, conformationally constrained, oxetane-modified oligonucleotides demonstrate efficient gene-silencing activity in a cellular system / J. B. Opalinska and A. M. Gewirtz -- In vivo potentialities of EWS-Fli-1 targeted antisense oligonucleotides-nanospheres complexes / Andrei Maksimenko ... [et al.] -- Endo-porter: a novel reagent for safe, effective delivery of substances into cells / James E. Summerton -- Tumor reversion: protein kinase a isozyme switching / Yoon S. Cho-Chung and Maria V. Nesterova -- Therapeutic potential of oligonucleotides expressing immunosuppressive TTAGGG motifs / Dennis M. Klinman ... [et al.] -- Breaking tolerance to tumors with dendritic cell-based immunotherapy / Ines Mende and Edgar G. Engleman --

Development of resistance to RNAi in mammalian cells / Zhi-Ming Zheng, Shuang Tang, and Mingfang Tao -- The development of bioactive triple helix-forming oligonucleotides / Michael M. Seidman ... [et al.] -- Transcription factor decoys: a new model for disease intervention / Michael J. Mann -- DNA damage produced by 125I-triplex-forming oligonucleotides as a measure of their succesful [sic] delivery into cell nuclei / Irina V. Panyutin -- Targeted genome modification via triple helix formation / Jennifer M. Kalish and Peter M. Glazer -- "Promoter array" studies identify cohorts of genes directly regulated by methylation, copy number change, or transcription factor binding in human cancer cells / Yipeng Wang ... [et al.] -- Application of expression genomics for predicting treatment response in cancer / Khew-Voon Chin ... [et al.] -- Stability regulation of mRNA and the control of gene expression / Chris Cheadle ... [et al.] -- Novel MDM2 p53-independent functions identified through RNA silencing technologies / Zhuo Zhang ... [et al.] -- Application of XIAP antisense to cancer and other proliferative disorders: development of AEG35156/ GEM 640 / Eric C. Lacasse ... [et al.] -- Induction of apoptosis by G3139 in melanoma cells / Luba Benimetskaya ... [et al.] -- Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy / Victor E. Marquez ... [et al.] -- Chemoprevention with protein kinase A RI[alpha] antisense in DMBA-mammary carcinogenesis / Maria V. Nesterova and Yoon S. Cho-chung.

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