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Protein structure and function /

Petsko, Gregory A.

Protein structure and function / Gregory A. Petsko, Dagmar Ringe. - 1st ed. - London : Sunderland, MA : Oxford : New Science Press ; Sinauer Associates ; Blackwell Pub., c2004. - xxii, 195 p. : col. ill. ; 28 cm. - Primers in biology .

including index

Includes bibliographical references (p. 181-188) and index.

Published by New Science Press and distributed in the U.S. and Canada by Oxford University Press

This text introduces general principles of protein structure, folding, and function, then goes beyond these basics to tackle the conceptual basis of inferring structure and function from genomic sequence. It is the first book in a series, Primers in Biology, employing a modular design in which chapters are divided into topics, each occupying one two-page spread that includes the relevant text, illustrations (in full color), definitions, and references.

The book has five chapters. The first is an introduction to the principles of protein structure and folding, with emphasis on proteins' biophysical properties. The second describes the principles of the main biochemical functions of proteins, namely binding and catalysis, with a short section on the properties of structural proteins. Chapter 3 covers the regulation of protein function, containing concise descriptions of all the regulatory mechanisms that operate on proteins, from pH to phosphorylation, with several sections on protein switches based on nucleotide hydrolysis. Chapter 4 introduces the principles whereby structure and function are deduced from sequence, with illustrative examples. The final chapter addresses how data on protein structure is gathered, interpreted, and presented.

Written for upper-level undergraduates and beginning graduate students, Protein Structure and Function is also be for working scientists needing an up-to-date introduction to the field.


0878936637 (Sinauer Associates) 9780878936632 0953918149 (New Science Press) 1405119225 (Blackwell Pub.)

2004351320

GBA3-W6400

101193781 DNLM


Proteins.
Proteins--Structure.
Proteins--Conformation.
Protein Conformation.
Proteins--physiology.

QP551 / .P3974 2004

572.633

2003 M-267 QU 55 / P498p 2004