MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03633cam a2200421 a 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
17863137 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20180625093959.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
130823s2013 nyua b 000 0 eng c |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
|---|
| LC control number |
2012277650 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780791860090 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
0791860094 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
1606504274 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781606504277 |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
(OCoLC)ocn828888913 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
BTCTA |
| Language of cataloging |
eng |
| Transcribing agency |
BTCTA |
| Modifying agency |
EYM |
| -- |
OCLCO |
| -- |
ORE |
| -- |
UMC |
| -- |
YDXCP |
| -- |
DLC |
| 042 ## - AUTHENTICATION CODE |
|---|
| Authentication code |
pcc |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
TP248.27.M53 |
| Item number |
G46 2013 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
660.62 |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Delvigne, Frank. |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
GFP whole cell microbial biosensors : |
| Remainder of title |
scale-up and scale-down effects on biopharmaceutical processes / |
| Statement of responsibility, etc |
Frank Delvigne ... [et al.]. |
| 246 3# - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
Green fluorescent protein whole cell microbial biosensors : |
| Remainder of title |
scale-up and scale-down effects on biopharmaceutical processes |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
1st ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
New York, N.Y. : |
| Name of publisher, distributor, etc |
ASME Press : |
| -- |
Momentum Press, |
| Date of publication, distribution, etc |
2013. |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE STATEMENTS |
|---|
| Date of production, publication, distribution, manufacture |
2013 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
43 p. : |
| Other physical details |
ill. (some col.) ; |
| Dimensions |
24 cm. |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Biomedical & nanomedical technologies - concise monograph series |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references (p. [36]-43). |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Interaction between fluid flow and microbial cells : importance of the operating scale -- Stochastic simulation of the displacement of microbial cells along concentration field -- Experimental results gained from the physiological response of GFP biosensors in scale-down conditions -- Another source of information : protein leakage and the study of the secretome. |
| 520 3# - SUMMARY, ETC. |
|---|
| Summary, etc |
Two strategies are usually considered for the optimization of microbial bioprocesses. The first one involves genetic or metabolic engineering of the target microbial strains in order to improve its production efficiency or its tolerance to adverse conditions. The second one is based on the chemical engineering improvement of the bioreactors and scaling-up rules. This work is more particularly dedicated to this second class of parameters. Recent developments in bioreactor technologies follow the scaling-out principle, i.e. carrying out several cultures in parallel with controlled conditions for screening purposes. Several mini-bioreactor concepts, i.e. bioreactor with working volume of 1 to 100 mL with controlling devices, have been developed following this principle. In general, chemical engineering similarities between conventional stirred bioreactors and their miniature equivalent are well characterized. However, the actual scaling-up rules are not able to cope with the complexity of the microbial stress response. Indeed, microbial stress response still remains not completely understood considering the process perturbations and the environmental fluctuations accompanying the scaling-up to industrial bioreactors. At this time, this kind of response can only be experimentally predicted by using scale-down bioreactors, i.e. lab-scale bioreactors designed in order to reproduce mixing imperfections that have to be expected at large-scale. However, the use of such an approach is time consuming and requires an experimented staff to elaborate the scaling-down protocols. Indeed, bioprocess development involves several steps which cannot be necessarily linked with each other considering the different cultivation equipment used-- |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Microbial biotechnology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Green fluorescent protein. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biosensors. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Delvigne, Frank. |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Biomedical & nanomedical technologies. |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
|---|
| a |
7 |
| b |
cbc |
| c |
pccadap |
| d |
2 |
| e |
ncip |
| f |
20 |
| g |
y-gencatlg |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Item type |
Books |
