Nouran Yehia Hamed Hemida

Antigen content as The Min factor In Avian Influence Vaccine Efficiency / Gp / Prof Mohamed Ali - Dr .Ahmed Gomaa - Dr Ahmed Kandeil - Msa university 2017 - 65 pages - Biotechnology DISTINGUISHED PROJECTS 2017 .

The vast majority of breast cancers are carcinomas that
originate from cells lining the milk-forming ducts of the
mammary gland. The human cytomegalovirus (HCMV) is a multifaceted highly host
specific betaherpesvirus that is regarded as asymptomatic or mildly pathogenic virus
in immunocompetent host. HCMV may cause acute and chronic complications in
immunocompromised individual. HCMV antigens and DNA have been detected in
tissue biopsies of breast cancers and sentinel lymph nodes and elevation in serum
HCMV IgG antibody levels have been reported to precede the development of breast
cancer in some women. The aim of the study is to evaluate the association of human
cytomegalovirus (HCMV) incidence and lymph node metastases in Egyptian breast
cancer patients. The project was carries out through testing of enrolled breast
cancer patients for presence or absence of HCMV IgG antibody in their blood
samples. Finally, correlation between incidence of HCMV DNA and lymph node
metastasis in breast cancer patients was assessed. Outcome of the study displays
that there is a statistical significance between HCMV-DNA and lymph node