Schüttler, Jürgen.

Modern anesthetics / Jürgen Schüttler, Helmut Schwilden, editors ; contributors J. Ahonen ... [et al.]. - 1st ed - Berlin : Springer, c2008. - xv, 498 p. : ill. ; 24 cm. - Handbook of experimental pharmacology, 182 0171-2004 ; . - Handbook of experimental pharmacology ; v. 182. .

Includes bibliographical references and index.

Part I Molecular Mechanisms of Anesthetic Action
Section Editor: B.W. Urban
The Site of Anesthetic Action .................... ........... . . 3
B.W. Urban
Inhibitory Ligand-Gated Ion Channels as Substrates
for General Anesthetic Actions.................................. 31
A. Zeller, R. Jurd, S. Lambert, M. Arras, B. Drexler, C. Grashoff,
B. Antkowiak, and U. Rudolph
Actions of Anesthetics on Excitatory
Transmitter-Gated Channels ..................................... 53
G. Akk, S. Mennerick, and J.H. Steinbach
Voltage-Gated Ion Channels ................ ................... 85
C. Nau
G-Protein-Coupled Receptors. .................................. 93
R.D. Sanders, D. Brian, and M. Maze
Part II Modern Inhalation Anesthetics
Section Editor: J.G. Bovill
Inhalation Anaesthesia: From Diethyl Ether to Xenon ................ 121
J.G. Bovill
General Anesthetics and Long-Term Neurotoxicity ................... 143
Special Aspects of Pharmacokinetics
of Inhalation Anesthesia ......................................... 159
J.E.A. Hendrickx and A. De Wolf
Inhalational Anaesthetics and Cardioprotection ..................... 187
N.C. Weber and W. Schlack
Non-Immobilizing Inhalational Anesthetic-Like
Compounds............ ............. .......... 209
M. Perouansky
Part III Modern Intravenous Anesthetics
Section Editor: E Camu
Propofol................................. 227
C. Vanlersberghe and E Camu
Pharmacokinetics and Pharmacodynamics of GPI 15715
or Fospropofol (Aquavan Injection) - A Water-Soluble
Propofol Prodrug ........................................... 253
J. Fechner, H. Schwilden, and J. Schiittler
Etomidate and Other Non-Barbiturates ............................ 267
C. Vanlersberghe and F Camu
Remifentanil and Other Opioids ............... .................. 283
ES. Servin and V. Billard
Ketamine ...................................................... 313
B. Sinner and B.M. Graf
Midazolam and Other Benzodiazepines ............................ 335
K.T. Olkkola and J. Ahonen
Part IV Pharmacokinetics-Pharmacodynamics Based
Administration of Anesthetics
Section Editor: D.R. Stanski
The Effect of Altered Physiological States
on Intravenous Anesthetics. .................. ................ 363
T.K. Henthorn
Anesthetics Drug Pharmacodynamics .............................. 379
P. Bischoff, G. Schneider, and E. Kochs
Defining Depth of Anesthesia ................ .................. 409
S.L. Shafer and D.R. Stanski
Target Controlled Anaesthetic Drug Dosing ........................ 425
H. Schwilden and J. SchUittler
Advanced Technologies and Devices for Inhalational
Anesthetic Drug Dosing ......................................... 451
J.-U. Meyer, G. Kullik, N. Wruck, K. Kitck, and J. Manigel
Hypnotic and Opioid Anesthetic Drug Interactions
on the CNS, Focus on Response Surface Modeling. ................... 471

9783540728139 (alk. paper) 3540728139 (alk. paper) 9783540748069 (eISBN) 3540748067 (eISBN)

2007936361

101464395 DNLM


Anesthetics.
Anesthetics--pharmacology.

RD78.3 / .M63 2008

615.781

W1 / HA51L no.182 2008 QV 81 / M689 2008