Pharmacokinetics and pharmacogenomics of cyclophosphamide in Rhabdomyosarcoma patients الحرائك الدوائية وعلم الأدوية الدوائي للسيكلوفوسفاميد في مرضى ساركومة العضلية // GP // DR.Rania Mohamed Labib // TA. Salma Wagih (2017-2018)

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[Nyera Hamdy Ibrahim 141797]

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Material type: Text

TextSeries: PHARMACY DISTINGUISHED PROJECTS 2018Publication details: Giza : MSA 2018Description: 77 P. 30 CMSubject(s):

Pharmacy -- Clinical Pharmacy -- Pharmacokinetics & pharmacogenomics

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Summary: renewing and asymmetric division that differentiate inside the body into for example , Somatic cells. Stem cell is possible to identify two large potential application fields of stem cells in diabetes mellitus: The reconstruction of β cell mass, and helps in the treatment of complications. Our target, find the mechanisms responsible for the effectiveness of bone marrow-derived mesnchymal stem cells in the suppression of DM Type 1. Experimental design: Eighteen male Albino Wistar rats divided into three groups , each Group having Six Rat Group I normal not diabetic and not suffering from any biochemical disorder, Group II Rats which are STZinduced diabetes group, Group III will be the Mesnchymal stem cells treated group MSCs (1×105 cells/rat) injected via tail veins in rats with STZ-induced diabetes. Blood glucose was measured spectrophotometry, Interleukin 6 and GLUT4 were measured by Elisa, insulin genes 1 and insulin genes 2 were measured by Real-time PCR. Insulin genes 1, insulin genes 2 and GLUT4 levels were significantly elevated in treated group compared to diabetic group (1). Interleukin 6 and blood glucose levels were significantly decreased in treated group compared to diabetic group. Mesnchymal stem cells may play an important role in treatment of T1DM

List(s) this item appears in: Pharmacy D. G. P 2017 / 2018

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Holdings
Item type	Current library	Call number	Status	Date due	Barcode
Distinguished Graduation Projects	Centeral Library Soft Copy located on library Cataloge	GP33PH2018CL.Pharmacy (Browse shelf(Opens below))	Available		81954

Pharmacy-Clinical Pharmacy

renewing
and asymmetric division that differentiate inside the body into
for example , Somatic cells. Stem cell is possible to identify two large
potential application fields of stem cells in diabetes mellitus: The
reconstruction of β cell mass, and helps in the treatment of complications.
Our target, find the mechanisms responsible for the effectiveness of bone
marrow-derived mesnchymal stem cells in the suppression of DM Type 1.
Experimental design: Eighteen male Albino Wistar rats divided into three
groups , each Group having Six Rat Group I normal not diabetic and not
suffering from any biochemical disorder, Group II Rats which are STZinduced
diabetes group, Group III will be the Mesnchymal stem cells
treated group MSCs (1×105 cells/rat) injected via tail veins in rats with
STZ-induced diabetes. Blood glucose was measured spectrophotometry,
Interleukin 6 and GLUT4 were measured by Elisa, insulin genes 1 and
insulin genes 2 were measured by Real-time PCR. Insulin genes 1, insulin
genes 2 and GLUT4 levels were significantly elevated in treated group
compared to diabetic group (1). Interleukin 6 and blood glucose levels
were significantly decreased in treated group compared to diabetic group.
Mesnchymal stem cells may play an important role in treatment of T1DM

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