000 02857nam a22002417a 4500
999 _c24941
_d24941
003 OSt
005 20190729073618.0
008 190721b ||||| |||| 00| 0 eng d
040 _cMSA
082 _a615.5
100 _aAhmed Yahia Abas 151465
245 _aDrug Prescribing Pattern in Intensive Care Unit of Al-Moalmeen Hospital in Egypt // GP // Dr. AbdelHamid El-Hawary // T.A. Salma Ayman (2018 - 2019)
260 _aGiza:
_bMSA,
_c2019
500 _aPharmacy - Clinical Pharmacy
520 3 _aThe intensive care unit is a special setting in hospitals where patients with severe, life-threating conditions are admitted, these patients mostly suffer from serious infections among other conditions which increases the mortality, morbidity and cost of hospitalization. The presented study was conducted to assess the drug utilization pattern mostly concerning the antibiotics prescription in the ICU. Aim is to Assess the treatment outcome specially for different combined therapies used for the treatment of gram-negative bacterial infections in the ICU and degree of improvement and period of staying in the ICU. Materials and Methods Retrospective study conducted in Intensive Care Unit of Al-Moalmeen Hospital. Analysis conducted on 54 cases admitted to ICU in six months. The data included: Age, Diagnosis, Vital signs, Treatment plan, and the outcome. APACHE Score was used to measure disease severity. Inclusion criteria: Patients with gram-negative bacteria infection from sputum, blood, and urine cultures. Exclusion criteria: Patients with Glasgow coma scale less than 9, End-stage metastatic malignant cancer patients, patients with APACHE II score more than 34, ventilated patients upon admission. The data analyzed by performing statistics on “Graph Pad Prism”. Results: Total 54 cases showed 62-gram negative bacteria cultures; 9 blood, 28 urine and 15 sputum cultures, also 10 swabs. These 62-cultures showed 31 cases E-coli, 14 cases klebsiella, 11 pseudomonas, and 6 cases Acinetobacter. 40 out 62 microorganisms treated with monotherapy including (Meronem/Forutm/Maixpime/Rocephin/Tazocin). 22 out 62 microorganisms treated with combined therapy including (Meropenem/Tavanic, Meronem/Ciprofloxacin, Meronem/Tigacylcine, Maxipime / Tavanic, Colistin/Gentamycin, and Ciprofloxacin /Amikin). Treatment with antibiotics monotherapy and combined therapy, empirical and targeted antibiotics therapy and Meronem antibiotic monotherapy and combined therapy didn’t show significant differences regarding mortality and survival rates.
650 _aDrug Prescribing
650 _aDrug utilization
700 _aNoran Mansour Boraik 15108
700 _aOmar Mohamed Nagy 151493
700 _aSamah Mohamed Hussien 153533
856 _uhttps://qrgo.page.link/yWFh9
_zFULL TEXT PRESS HERE
942 _2ddc
_cD.GP