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008 040622s2004 enka b 001 0 eng c
010 _a 2004351320
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_2DNLM
020 _a0878936637 (Sinauer Associates)
020 _a9780878936632
020 _a0953918149 (New Science Press)
020 _a1405119225 (Blackwell Pub.)
035 _a(OCoLC)ocm53181467
040 _aNLM
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050 0 0 _aQP551
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060 0 0 _a2003 M-267
060 1 0 _aQU 55
_bP498p 2004
082 0 0 _a572.633
_222
100 1 _aPetsko, Gregory A.
245 1 0 _aProtein structure and function /
_cGregory A. Petsko, Dagmar Ringe.
250 _a1st ed.
260 _aLondon :
_bNew Science Press ;
_aSunderland, MA :
_bSinauer Associates ;
_aOxford :
_bBlackwell Pub.,
_cc2004.
300 _axxii, 195 p. :
_bcol. ill. ;
_c28 cm.
440 0 _aPrimers in biology
502 _aincluding index
504 _aIncludes bibliographical references (p. 181-188) and index.
520 _aPublished by New Science Press and distributed in the U.S. and Canada by Oxford University Press This text introduces general principles of protein structure, folding, and function, then goes beyond these basics to tackle the conceptual basis of inferring structure and function from genomic sequence. It is the first book in a series, Primers in Biology, employing a modular design in which chapters are divided into topics, each occupying one two-page spread that includes the relevant text, illustrations (in full color), definitions, and references. The book has five chapters. The first is an introduction to the principles of protein structure and folding, with emphasis on proteins' biophysical properties. The second describes the principles of the main biochemical functions of proteins, namely binding and catalysis, with a short section on the properties of structural proteins. Chapter 3 covers the regulation of protein function, containing concise descriptions of all the regulatory mechanisms that operate on proteins, from pH to phosphorylation, with several sections on protein switches based on nucleotide hydrolysis. Chapter 4 introduces the principles whereby structure and function are deduced from sequence, with illustrative examples. The final chapter addresses how data on protein structure is gathered, interpreted, and presented. Written for upper-level undergraduates and beginning graduate students, Protein Structure and Function is also be for working scientists needing an up-to-date introduction to the field.
650 0 _aProteins.
650 0 _aProteins
_xStructure.
650 0 _aProteins
_xConformation.
650 1 2 _aProtein Conformation.
650 2 2 _aProteins
_xphysiology.
700 1 _aRinge, Dagmar.
906 _a7
_bcbc
_cpccadap
_d2
_encip
_f20
_gy-gencatlg
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_cBK