MARC details
| 000 -LEADER |
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| fixed length control field |
02764nam a22002537a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20190805094053.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190801b ||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
MSa |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
547 |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Ahmed Mohamed 151639 |
| 245 ## - TITLE STATEMENT |
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| Title |
Nanoformulation and Pharmacological Evaluation of Antiaging Herbal Product(s) (Nanostructure lipid carrier, NLC) // GP / / Dr. Reham Amer // Dr. Pakinam Zikry (2018 - 2019) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
GIZA : |
| Name of publisher, distributor, etc. |
MSA, |
| Date of publication, distribution, etc. |
2019. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
41 P. |
| 440 ## - SERIES STATEMENT/ADDED ENTRY--TITLE |
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| Title |
PharmaciesDISTINGUISHED PROJECTS 2019 |
| 500 ## - GENERAL NOTE |
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| General note |
Pharmacy - Organic Chemistry |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Skin aging is a complex of biological process which affected by constant exposure to ultraviolet<br/>(UV) irradiation with subsequent generation of reactive oxygen species leading to collagen<br/>deficiency and eventually skin wrinkling. Different techniques were reported for treatment;<br/>however the application of anti-aging creams is still the best choice among various treatment<br/>methods to their nourishing effect. Apart from that herbal formulation has widely demanded in<br/>the world market for its safety. In the present study lipid nanoparticles (LNPs) are used in the<br/>formulation of anti-aging Citrus Sinensis (CS) cream due to its safety and biocompatibility of its<br/>lipid components. Eight different formulations of CS-LNPs were prepared and optimized using<br/>3 full factorial designs. Three factors were evaluated drug concentration (X1), homogenization<br/>speed (X2) and nanoparticle type (X3). Different parameters were measured including; zeta<br/>potential (ZP), polydispersity index (PDI), particle size, entrapment efficiency (EE %) and skin<br/>occlusion test. Morphological study by using scanning electron microscopes (SEM) confirms the<br/>nanometric size of the prepared formulations with spherical and smooth surface. It was suggested<br/>that the optimized formulation (F7) was found to have (245μm) particle size, (91.065%)<br/>Entrapment Efficiency, and (91.385) Occlusive effect. In vitro permeation study of the optimized<br/>formulation through synthetic membrane showed prolonged release of medication within 24 hrs.<br/>Finally, it can be concluded that the prepared anti-aging CS/NLC cream was safe, convenient,<br/>and effective carrier to deliver the herbal medication it also showed better penetration into the<br/>skin with a significant anti-aging effect thus it will be a promising product in skin care<br/>cosmetics. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Nanoformulation and Pharmacological |
| General subdivision |
(Nanostructure lipid carrier |
| Chronological subdivision |
Antiaging Herbal Product(s) |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Asim Reda 151355 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Manar Tarek 150761 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Sara Yasser 151317 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1wyhUy9j78z2i0OHpOvKrd7k1dmzM3QAr/view">https://drive.google.com/file/d/1wyhUy9j78z2i0OHpOvKrd7k1dmzM3QAr/view</a> |
| Public note |
FULL TEXT PRESS HERE |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Distinguished Graduation Projects |
